This module offers a comprehensive introduction to Factor VII Deficiency, a rare bleeding disorder with a highly variable clinical presentation. You will explore its definition and prevalence, the circumstances and symptoms under which it typically manifests, and the step-by-step process for biological and molecular diagnosis. The module also provides practical guidance on treatment strategies, including perioperative management, prophylaxis, and the careful balance between bleeding and thrombotic risks with real-world case studies help contextualise the theoretical content.