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Inhibitor Development in Gene Therapy for Haemophilia

Gene therapy is changing the treatment landscape of haemophilia, but inhibitor development remains a key clinical and scientific question. This webinar will provide an integrated overview of the immunological mechanisms involved in inhibitor development, insights from real clinical cases following gene therapy, and a critical review of current clinical studies addressing the relevance of inhibitors in this context. Leading experts will discuss emerging evidence, clinical challenges, and what these findings may mean for future treatment strategies in haemophilia gene therapy.

Agenda

  • Overview of Clinical Gene Therapy Studies and the Relevance of Inhibitor Development
    Davide Matino
  • Immunological Processes Relevant to Inhibitor Development in Gene Therapy
    Sebastien Lacroix-Desmazes
  • Clinical Cases of Inhibitor Development in Gene Therapy for Haemophilia
    Guy Young