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Module 17: Inherited Factor VII Deficiency

This module offers a comprehensive introduction to Factor VII Deficiency, a rare bleeding disorder with a highly variable clinical presentation. You will explore its definition and prevalence, the circumstances and symptoms under which it typically manifests, and the step-by-step process for biological and molecular diagnosis. The module also provides practical guidance on treatment strategies, including…

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Critical Juncture in Hemophilia Treatment: Global Organizations Issue Urgent Call to Action

In light of recent decisions by several pharmaceutical companies to pause, scale back, or discontinue their haemophilia gene therapy programs, the International Society on Thrombosis and Haemostasis (ISTH), the World Federation of Hemophilia (WFH), and the European Association for Haemophilia and Allied Disorders (EAHAD) have issued a formal Call-to-Action. The statement highlights the importance of…

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Statement on the ISTH clinical practice guideline for treatment of congenital haemophilia A&B

The European Association for Haemophilia and Allied Disorders (EAHAD) commends the International Society's on Thrombosis and Haemostasis (ISTH) initiative to publish evidence-based guidelines. These guidelines have been subject to considerable discussion, with numerous clinicians and organisations expressing concerns, and we acknowledge the disquiet within the wider community. Nevertheless, it is crucial to remember that guidelines are…

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